Abstract
Backgroundi¼Stress Cardiomyopathy (SCM) is an increasingly reported disease as a syndrome of acute, severe, but reversible, which is commonly triggered by an acute strong physical or emotional stress. But little is known whether chronic diseases may contribute to the occurrence of SCM. Methodi¼The case reports about SCM from January 1998 to May 2014 were searched in the PubMed using the Medical Subject Headings: “tako-tsubo cardiomyopathy” or “stress cardiomyopathy” or ‘‘ampulla syndrome’’ or ‘‘apical ballooning syndrome’’ or ‘‘broken heart syndrome’’. The publications were excluded which didn’t meet the inclusion criteria. SCM patients with and without chronic diseases were CD group and NCD group, respectively. The CD group was further classified into nine subgroups according to underlying chronic diseases. The circulatory diseases group which had the highest percentage in CD group was analyzed further. Results: 1331 literatures about SCM were collected, in which 1052 documents were eligible. In these documents, 1206 patients were reported, 795 had chronic diseases, 411 had no significant past medical history. The average age in NCD group was younger than that in CD group (57.3 ± 0.9 years versus 62.4 ± 0.6 years, P < 0.01). The number of SCM patients with Circulatory diseases was the most, then was Endocrine, Digestive, Respiratory, etc. The proportion of hypertension was 74.0% in circulatory diseases followed by dyslipidemia 29.3%, arrhythmia 10.1%, coronary artery disease 5.8%, etc. Conclusioni¼According to our results, the chronic diseases, especially hypertension, rose the rate of occurrence and delayed the onset age of SCM.
Highlights
Stress Cardiomyopathy (SCM), called Tako-tsubo cardiomyopathy, broken heart syndrome or apical ballooning syndrome, is commonly triggered by an acute strong physical or emotional stress
Case reports about SCM from January 1998 to May 2014 were searched in Pubmed by using the Medical Subject Headings with no language restrictions:‘‘Tako-tsubo cardiomyopathy’’ or ‘‘stress cardiomyopathy’’ or ‘‘ampulla syndrome’’ or ‘‘apical ballooning syndrome’’ or ‘‘broken heart syndrome”
In female, the numbers of SCM patients were quite different among age groups, being highest in group 60 ~ 69 and 70 ~ 79
Summary
Stress Cardiomyopathy (SCM), called Tako-tsubo cardiomyopathy, broken heart syndrome or apical ballooning syndrome, is commonly triggered by an acute strong physical or emotional stress. The SCM has a very low death rate compared with acute coronary diseases or heart failure [1]. High concentrations of epinephrine is thought of as the main cause of the disease [4,5,6], which was supported by several scholars reported that iatrogenic epinephrine could induce SCM [7,8]. Stress Cardiomyopathy (SCM) is an increasingly reported disease as a syndrome of acute, severe, but reversible, which is commonly triggered by an acute strong physical or emotional stress. Little is known whether chronic diseases may contribute to the occurrence of SCM
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