Abstract
Acute oxygen starvation of the brain causes structural and metabolic disorders in neurons, leading to their death. When studying the brain of rats under conditions of strangulation asphyxia, modeled by compression of the trachea with a ligature, the presence of anoxic damage to neurons in the occipital lobe cortex was revealed. After 30 minutes of asphyxia, the neurons acquired an elongated shape, losing their roundness, without changing in size. With 60 minutes of asphyxia, there was a decrease in the area of neurons, which worsened by 24 hours of asphyxia, but there was no change in the shape of neurons. During the studied periods of asphyxia, an increase in the number of hyperchromic wrinkled neurons was observed with a decrease in the number of normochromic neurons and their complete disappearance by 24 hours of asphyxia.
Published Version
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