STORM-based multi-functional carbon dots for investigating HS- interaction with mitochondria in living cells

Abstract

By investigating the interaction between subcellular components using visualization techniques, pathological processes can be intuitively analyzed to reveal the origins of associated disorders more efficiently. Based on the Stochastic optical reconstruction microscopy (STORM) imaging nanoscopy, this study is the first to achieve a higher resolution and high signal-to-background ratio image of living cells by employing photoblinking carbon dots (P-CDs). Accordingly, this example can be used to explore the interaction between subcellular structures more precisely and clearly. Thus, the current study provides a potent method for visualizing the etiology of associated disorders.