Abstract
Background: Caffeine is routinely used in preterm infants for apnea of prematurity. The use of caffeine in preterm infants also improves respiratory and neurodevelopmental outcomes. In the past, the standard dosage of caffeine was 5mg/kg/day. More recently, a higher dose of caffeine is used in preterm infants as it has a wide therapeutic window. Because of the long half-life of caffeine, preterm infants are usually monitored for 5 days after discontinuation of caffeine to assess for possible recurrence of apnea. However, with the use of a higher …
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