Abstract
Background: Thyroid disorders are amongst the most common endocrine diseases in India. Numerous studies from various countries differ in their prevalence estimates for both hypothyroidism and hyperthyroidism. There is however a paucity of data from the rural areas. The present study was conducted to find out the prevalence of thyroid disorders among the people of Wardha district of Maharashtra. Materials and Methods: This is the observational, retrospective study conducted in Acharya Vinobha Bhave Rural Hospital, Sawangi (Meghe), Wardha. In total, 1905 patients visiting to hospital and suspecting of thyroid disorders were screened for thyroid function. Thyrotrophin (TSH), free triiodothyronine (FT3), and free tetraiodothyronine (FT4) in human serum were quantitatively estimated by a microplate immunoenzymetric assay. Results: Of the 1905 total subjects in the age range 10-80 years, 35.7% had thyroid dysfunction and 64.3% had euthyroidism; 21.7% had hypothyroidism (6.9% clinical, 14.8% subclinical); 2.3% had hyperthyroidism (1.1% clinical and 1.2% subclinical), while 11.6% had mildly suppressed TSH with normal FT4. Conclusion: The prevalence of clinical (75%) and subclinical hypothyroidism (71%) and clinical (66%) and subclinical (70%) hyperthyroidism was high in the 21-50 year age group with decreasing trend towards end. Also, the prevalence of mildly suppressed TSH was high in the 21-50 year age groups, which is 65%. This means that major burden of thyroid disorders is on reproductive age groups. This problem must be addressed immediately to avoid deleterious effect of abnormal thyroid dysfunction on the patients as well as on their offspring.
Published Version
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