Abstract
The subject of herbal drug standardization is massively wide and deep, there is so much to know and so much seemingly contradictory theories on the subject of herbal medicine and its relationship with human physiology and mental function. India needs to explore the important formulations in the classical ayurvedic texts. This can be achieved only if the herbal products are evaluated and analysed using sophisticated modern techniques of standardization such as UV-Visible, TLC, HPLC, HPTLC, etc. The present paper reports on Standardization and Comparative Analysis of Different Marketed Formulation of Agnimukh Churna, a poly herbal ayurvedic medicine used in treatment of anorexia, indigestion, constipation, spleen disorders, non bleeding hemorrhoids’ and abdominal pain.
 Agnimukh Churna was prepared as per Ayurvedic text of Yogaratnakara, India. In-house preparation and two marketed have been standardized on the basis of organoleptic characters, physical characteristics, physico-chemical properties, TLC and HPLC for the estimation of marker compound Piperine. The set parameters were found to be sufficient to evaluate the Churna and can be used as reference standards for the quality control/quality assurance laboratory of a Pharmaceutical house.
 Keywords: Agnimukh Churna; Physicochemical parameters; organoleptic characters; Polyherbal formulation; Standardization; Piperine
Highlights
STANDARDIZATION AND COMPARATIVE ANALYSIS OF DIFFERENT MARKETED FORMULATION OF AGNIMUKH CHURNA Sharath M.V.*, S.M
The present paper reports on Standardization and Comparative Analysis of Different Marketed Formulation of Agnimukh Churna, a poly herbal ayurvedic medicine used in treatment of anorexia, indigestion, constipation, spleen disorders, non bleeding hemorrhoids’ and abdominal pain
An attempt has been made to standardize Agnimukh Churna; an ayurvedic formulation which is mentioned in classical ayurvedic text of Yogaratnakara, The ingredients of agnimukh Churna include Shwet Jirka (Cuiminum cyminum), Shunti (Zingibere officinale), Kale namak (Black salt) Kali marich (Piper nigrum) Nimbusatva (Citric acid), Saindavalavana (Rock salt), Pudina Satva, and is used in treatment of anorexia, indigestion, constipation, spleen disorders, non bleeding hemorrhoids and abdominal pain.[3]
Summary
STANDARDIZATION AND COMPARATIVE ANALYSIS OF DIFFERENT MARKETED FORMULATION OF AGNIMUKH CHURNA Sharath M.V.*, S.M. India needs to accept the challenge present herbal formulations in a way accepted by scientific community. This can be achieved only if the herbal products are evaluated and analysed using sophisticated modern techniques of standardization.[1]. Standardization is a system to ensure that every packet of medicine that is being sold has the correct substances in correct amount and shall induce intended therapeutic effect. It is a requirement for ayurvedic formulation to undergo the quality tests in order to compete in international market so as to satisfy requirements of regulatory agencies of respective countries[2]. Three formulations, one in-house preparation and two samples from different manufacturers were procured and subjected to its organoleptic, physical, physico chemical analysis, TLC and chemical properties
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