Abstract
Studies of sputum viscosity from patients with cystic fibrosis and other diseases showed that in cystic fibrosis mucoid sputum was less viscous than that produced by patients with other respiratory diseases. Unlike bronchitic sputum, the viscosity of cystic fibrosis sputum increased markedly with purulence. Evidence is discussed to suggest that factors in addition to sputum viscosity may be of importance in initiating pulmonary disease in cystic fibrosis.
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