Abstract
This chapter focuses on the recent progress in defining the effects of the transfer factor on immunologic and inflammatory responses. There are several reports in which immunodeficient patients with subnormal numbers of circulating T-cells have shown increases in the percentages of E-rosette-forming lymphocytes after receiving the transfer factor. From observations on patients with immunodeficiency diseases, it appears that the most consistent consequence of transfer factor therapy on lymphocyte responses is the appearance of lymphokine-producing cells. There seems to be a quantitative disparity between the relative ease of obtaining lymphokine production by lymphocytes from persons who have received transfer factor in vivo and the inconsistent results obtained when lymphocytes are treated with transfer factor in vitro . The polypeptide model can generate large numbers of reactive combinations.
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