Abstract

The Journal of the National Science Foundation of Sri Lanka publishes the results of research in all aspects of Science and Technology. The journal also has a website at http://www.nsf.gov.lk/. 2021 Impact Factor: 0.682The JNSF provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.

Highlights

  • T-cells [ Cytotoxic T-Lymphocytes (CTL) ] play a major role in the adaptive immune system of vertebrates in defense against viral, bacterial and fungal infections

  • When does the activation of a T-cell become hard? If the T-cells fail to respond to invading pathogens within reasonable time, the activation of a T-cell becomes hard

  • The role of T-cell activation when the CD4 molecule is inhibited has been reported by Irvine and Davis (Irvine & Davis, 2002) where this probability lies in the range 0.001 - 0.002

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Summary

Introduction

T-cells [ Cytotoxic T-Lymphocytes (CTL) ] play a major role in the adaptive immune system of vertebrates in defense against viral, bacterial and fungal infections. # thes eas sumptions toaqueue with Poisson input Stochastic approaches to modelling the T-cell λ = koff |C * where, |C*| = number of fully phosphorylated APC interaction have been considered in the past pMHC-TCR complexes and Poisson output with rate (Chan et al, 2001: Noest, 2000; van den Berg et al, μx (t): 2001).

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