Abstract
Introduction. In patients with extra-adrenal malignancy, an adrenal mass necessitates investigating the possibility of metastatic tumor. Curable adrenal metastasis are considered as a rare event. Case report. A 52-year-old male suffering from lower esophageal adenocarcinoma with a solitary left adrenal metastasis is presented herein, who underwent concomitant transhiatal esophagectomy and left adrenalectomy. The patient remains disease-free 18 months later. Discussion. Adrenal metastases mostly occur in patients with lung, kidney, breast, and gastrointestinal carcinomas. Primary esophageal adenocarcinoma gives adrenal metastatic deposits according to autopsy series with an incidence of about 3%–12%. When no other evidence of metastatic disease in cancer patients exists, several authors advocate adrenalectomy with curative intent. Isolated cases of long-term survival after resection of solitary adrenal metastasis from esophageal adenocarcinoma, like in our case, have been reported only as case reports. Conclusion. This study concludes that surgical resection may result in survival benefit in selected patients with solitary adrenal metastasis from esophageal adenocarcinoma.
Highlights
In patients with extra-adrenal malignancy, an adrenal mass necessitates investigating the possibility of metastatic tumor
Radical surgical resection of the primary tumor associated with excision of the adrenal metastasis results in long-term survival
We present a case of a 52-yearold male suffering from esophageal adenocarcinoma with solitary metastasis to the left adrenal gland treated with concomitant transhiatal esophagectomy and left adrenalectomy
Summary
In patients with extra-adrenal malignancy, staging imaging modalities frequently reveal adrenal masses and require exclusion of the possibility of metastatic tumor spread [1]. Adrenal metastatic tumor usually indicates advanced malignancy and disseminated disease for most cancer patients, and especially for patients with primary esophageal cancer [2]. Radical surgical resection of the primary tumor associated with excision of the adrenal metastasis results in long-term survival. We present a case of a 52-yearold male suffering from esophageal adenocarcinoma with solitary metastasis to the left adrenal gland treated with concomitant transhiatal esophagectomy and left adrenalectomy. In his follow-up visits, he remains disease-free eighteen months later. A short review of the literature with reference to similar cases is attempted
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