Abstract
Since the independent discovery of the formation of mesostructured silica using surfactants as structure directing agents by several groups in the early 1990s, these materials have found important application in the area of catalysis, separation technology and, most recently, as biomaterials. Among all the silica based materials that have been investigated, mesoporous silica nanospheres with well-defined structures and surface properties are very promising for various biomedical applications. In this chapter we first provide a brief history along with the general synthesis procedure of mesoporous silica materials. This is followed by a description of the synthesis to obtain the mesoporous silica based microspheres and nanospheres. We also discuss the physical and chemical properties along with the general characterization techniques used for these materials. Particular attention is paid towards the applications as biomaterials.
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