Significance of i-Scan in the diagnosis of Barrett's esophagus

Abstract

Objective To evaluate the value of i-Scan in the diagnosis of Barrett's esophagus. Methods 52 patients diagnosed with Barrett's esophagus by gastroscopies and pathological examinations were observed under the ordinary edoscopy and i-Scan respectively.Besides,the Barrett's esophageal mucosa were classified by Endo with i -scan mode, the target lesions was taken to be biopsied and pathologically examined. Results (1)In the 52 patients,mucosal lesions were found in 46 cases(88.5%) under i-Scan and 35 cases(67.3%) under ordinary edoscopy respectively,mucosal lesion detection rate in i-Scan was significantly higher than normal white mode(P< 0.01).In the 33 patients which found mucosal lesions in the two modes,the definition of lesion margins,morphology of lesion cryptaeand mucosa capillaries revealed by i-Scan were superior to that by white lighted endoscopy(P< 0.05);(2)Under i-scan mode,the detection of specific intestinal metaplasia(SIM) of typeⅣ,type V in sensitivity, accuracy,specificity were respectively 90.0%,93.5%,94.4%. Conclusion i-Scan is very easy to operate and has a clear lesion of Barrett's esophagus,which helps to target the lesion at pathological biopsy. Key words: Gastroscopy; Barrett Esophagus; Coloring Agents; Diagnosis