Abstract
TROMEXAN, a new anticoagulant, has recently been accepted for general use. Chemically, it is described as ethyl biscoumacetate (3,3′ carboxymethylenebis- [4-hydroxycoumarin] ethyl ester). It is most widely recognized as Tromexan but is also known as Pelentan, B.O.E.A. and D.E.A. Dicumarol1 and Tromexan2 are related members of the coumarin series of drugs. Each is presumed to act in similar fashion, by interfering with the normal production of prothrombin by the liver. The exact mode of action is as yet unknown.3 , 4 The possibility of hemorrhage after Dicumarol administration is well known, and precautions for its use have been repeatedly stressed.5 6 7 Utilizing an . . .
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