Seroprevalence of Rubella virus and cytomegalovirus infections in infertile women in Baghdad city

Abstract

Infertility in women ranked the eighth highest serious global disability and thus the need for health care is conventional to the rights of personal with disability. Infectious agents can impair reproduction as well as many important human vital functions. Cytomegalovirus (CMV) and Rubella viruses are the commonest viral infections in prenatal period and they are the leading causes for congenital infections that may ends with fetal death and spontaneous abortion. This study was constructed on infertile women attendingAbdull-Majeed private hospital in Baghdad of the period from 6/2014 to 11/2015. Eighty-five infertile women aged from 18 -40 years tested for the presence of recent or past infection with cytomegalovirus or rubella virus. Another forty-two pregnant women with no history of abortion were included as normal control. For the purpose of comparison, cases were distributed on two age groups. Both groups were tested for the presence of anti-CMV and anti-rubella antibodies, IgM and IgG by using enzyme linked immunosorbent assay (ELISA) (mono bind Microplate reader awareness, US). About 54.1% of infertile women found to be infected with CMV compared to 60.2% of normal control, while 34.1% of infertile women found to be infected with Rubella virus compared to 42.8% of normal control. Absence of anti-rubella IgG (indicator of past infection or vaccination) in 69.4% of infertile women compared to 62.9% of normal control