Abstract
A liquid chromatographic method using dual-electrode detection has been developed for determination of physostigmine in biological fluids. The limit of detection is in the order of 25–50 pg mol −1 of plasma. A high sample throughput is obtained by a single solvent extraction step and autoinjection into the chromatograph. Data following oral doses of physostigmine are presented.
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More From: Journal of Chromatography B: Biomedical Sciences and Applications
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