Abstract

The article is a survey of some plant extracts that possess ability to restore metabolic disturbances evoked by chronic stress. Chronic stress triggers a number of common illnesses, including depression, chronic physical and mental fatigue, neuroses, cardiovascular diseases, ulceration of stomach and intestine, diabetes mellitus, obesity and alcohol abuse. One of the early consequences of chronic stress is the decrease of functional activity of immune system that reduces resistance against infections, allergies, asthma, autoimmune disorders, rheumatoid arthritis. The initial stages of chronic stress consequences are suppression of immune system, disturbances of hormonal balance, hydrocarbon, lipid, and energy metabolism. Applicability of the extracts from Leuzea carthamoides, Rhodiola rosea, Eleutherococcus senticosus, Schizandra chinensis and their combination “AdMax” to counteract the initial stages of chronic stress consequences is considered.

Highlights

  • The article is a survey of some plant extracts that possess ability to restore metabolic disturbances evoked by chronic stress

  • The most characteristic common illnesses triggered by chronic stress include chronic physical and mental fatigue, neuroses, depression, cardiovascular diseases

  • Some data indicate that active compounds of adaptogenic plant extracts act on body cells on the level of hormonal receptors and membrane proteins of corresponded signaling pathways [5]

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Summary

CHRONIC STRESS CONSEQUENCES

Many functions of various tissues in the organism, especially endocrine glands, are controlled by division of the brain called hypothalamus. One of the early consequences of chronic stress is decrease of functional activity of immune system. Some data indicate that active compounds of adaptogenic plant extracts act on body cells on the level of hormonal receptors and membrane proteins of corresponded signaling pathways [5]. Biological effectiveness of concrete plant compound is determined by level of its affinity to the responsive membrane protein. It is important, that most of biologically active compounds isolated from adaptogenic plant extracts demonstrate lesser biological effect than the effect of whole extract. The adaptogenic properties of the extracts from four plants, that have been undergone most careful and rigorous testing by scientists and physicians, are described below Extracts from these plants are constituents of the nutritional supplement “AdMax”

Leuzea carthamoides Extract
Rhodiola rosea Extract
Eleutherococcus senticosus Extract
Brekhman at the Far East Center of the Russian
Individual eleutherosides isolated from
Schizandra chinensis Extract
ADMAX Influence on Immune System
Enhancing of Sexual Function by AdMax
Findings
AdMax Capability to Modulate Gene Expression
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