Abstract

The cardiac Left Ventricle (LV) segmentation is still challengeable due to the complex anatomical structure surrounding the LV and intensity overlaps caused by intensity inhomogeneities, which widely exists in cardiac Magnetic Resonance (MR) images. To overcome these problems, a shape prior constrained two-layer level set method is proposed to simultaneously extract the endocardium and epicardium of the LV from cardiac short-axis MR images. The proposed method is validated on MR images from the LV challenge of MICCAI 2009. Quantitative and qualitative experiments and clinical metrics demonstrate that the proposed method has better performance than some representative methods in term of Dice Similarity Coefficient (DSC), Average Perpendicular Distance (APD), Ejection Fraction (EF), and LV mass. Experimental results demonstrate that the proposed method has the priority of preserving cardiac anatomical structure and improving segmentation accuracy.

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