Abstract
ASAP1 is an Arf GTPase Activating Protein (ArfGAP) that participates in the regulation of actin-dependent membrane traffic and organelle structure by stimulating the activity of the small GTPase Arf1 at the membrane, thereby converting Arf1·GTP to Arf1·GDP. The core catalytic domain of ASAP1—referred to as ASAP1-PZA—is composed of a Pleckstrin homology (PH) domain ([325-451]—ASAP1, ∼14 kDa), immediately N-terminal to the catalytic Arf GAP domain ([458-724]—ASAP1 or ZA domain, ∼30 kDa); these two domains are connected by a short linker.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
