Abstract
Objective To observe the sedation efficacy of application of intranasal dexmedetomidine in lacrimal passage probing of infants. Methods Forty-seven eyes of 40 infants received lacrimal passage probing. All cases were randomly divided into 2 groups.Group A, 23 eyes of 20 cases, recieved application of dexmedetomidine intranasally with a dose of 2 μg/kg at 30 min before entering the operating room. Group B, 24 eyes of 20 cases, did not receive any treatment.All patients in the two groups treated with lacrimal passage probing after anaesthesia with 0.4% oxybuprocaine hydrochloride.The various states of infants after entering the operating room were graded. Results Group A was significantly better than those of group B at the sedation score, emotion state, parental separation and acceptance of surgical operation(P<0.05). The complications occurred in group B in 7 cases and 2 cases in group A(P<0.05). Conclusion Application of intranasal dexmedetomidine in lacrimal passage probing can improve surgical coordination of infant and reduce children’s surgical complications. Key words: Dexmedetomidine; Sedation; Infant; Lacrimal passage probing
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