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https://doi.org/10.1021/jo4017524
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Cite Journal: The Journal of Organic Chemistry |  Publication Date: Oct 8, 2013 |
 Citations: 40 |
Affiliation: Western University
Treatment of indolylmethyl Meldrum's acids with catalytic scandium triflate and a variety of nucleophiles results in the nucleophilic displacement of the Meldrum's acid moiety via a gramine-type fragmentation. The reaction is useful for the generation of heterocyclic compounds of significant molecular complexity.
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