Abstract

Then each slide was processed to be stained at the department of cytopathology and reviewed by cytopathologists to assess the specimen adequacy. Results: Seventy-eight specimens were collected from 33 patients. Aspirated lesions were as follows: 46 pancreas (59.0%), 14 intra-abdominal lymph nodes (17.9%), other intra-abdominal organ (17.9%) and mediastinal lymph node (5.1%). Of these, malignancies were 69.2%, borderline malignancies 3.8% and benign lesions 26.9%. The positive predictive value (PPV) of non-bloody white core for prediction of specimen adequacy was 95.2% and the PPV of bloody core with white spots was 100.0%. Among adequate sample slides, non-bloody white core was observed in 60.6% and bloody core with white spots were observed only in 28.8%. Combined criteria of non-bloody white core and bloody core with white spots, presence of white core/spots showed sufficient value of sensitivity (89.4%), specificity (83.3%) and PPV (96.7%) for predicting sample adequacy. Conclusions: sVisual assessment of specimen adequacy seems to be very useful during EUS-FNA. Presence of white core/spots showed very high PPV. By using morphologic criteria with high PPV, it may be possible to reduce the number of needle pass and procedural time in general fields of practice. In future, studies for decreasing interobserver variability should be followed.

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