Abstract
Objective: To assess the outcomes of hearing and vertigo in patients with Meniere’s disease who were treated with intratympanic methylprednisolone. Study Design: Retrospective study. Setting: Tertiary referral hospital. Methods: In our study with 151 patients [191 ears] were diagnosed as Menieres as per 1995 AAO-HNS guidelines. As an office based procedure these patients were treated with intratympanic methyl prednisolone. Results: There was a 98.6% improvement in the vertigo control rate, a 73.82% improvement in hearing and 29.31% had a definitive improvement in tinnitus. Conclusion: We conclude from our study that intratympanic steroid injection significantly controls vertigo, tinnitus and improves hearing in Meniere’s disease with minimal complications. Hence, it can be tried as a first line treatment for patients with Meniere’s disease.
Highlights
Meneire’s disease is first described by Prosper Meniere, as inner ear disorder characterised by vertigo, hearing loss, tinnitus and aural fullness
The AAO-HNS criteria were used to quantify the control of vertigo: the number of definite spells of vertigo during the 6 months previous to treatment with intratympanic methylprednisolone was compared with the number of episodes 6 months after treatment
We conclude from our study that intratympanic steroid injection significantly controls vertigo, tinnitus and improves hearing in Meniere’s disease with minimal complications
Summary
Meneire’s disease is first described by Prosper Meniere, as inner ear disorder characterised by vertigo, hearing loss, tinnitus and aural fullness. The pathogenesis of the disease is not understood but other etiological factors attributed to Meneire’s disease are autoimmune, viral infection like varicella zoster, herpes simplex virus and cytomegalovirus, or as a consequence of other inner ear disorders like infectious labrynthitis, noise induced hearing loss or vestibular schwannoma [1]. (2016) Role of Intratympanic Steroids in the Management of Meniere’s Disease—A Review of 151 Cases. Intratympanic steroid injection is a promising modality for treating patients with Meniere’s disease. As the disease is immune mediated, studies suggest treatment with intratympanic steroids improve the function of normal stria vascularis [4], protects the inner ear and reverses the hearing loss [5]
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