Abstract
Gout is a metabolic disorder that is characterized by a deposition of monosodium urate crystals in the joint or soft tissue. Gout manifestations in head and neck region are rare, and larynx is an infrequently affected location. We recently managed a case of a gouty tophus over the larynx. A 65-year-old male with a long history of gout without medical control. He has suffered from increasing hoarseness for six months. Laryngoscopy revealed a mass lesion over the right vocal process region without vocal paralysis. Laryngo-micro-surgery biopsy was taken, and pathology confirmed laryngeal gouty tophus without evidence of malignancy.
Highlights
Gout, known as metabolic arthritis, is a purine metabolic disorder caused by uric acid accumulation in and around joints
The larynx is an infrequently affected location, gouty involvement of the larynx can lead to significant laryngeal symptoms
Laryngoscopy revealed a hemispherical mass with a smooth surface over the right vocal process and pathology showed laryngeal gouty tophus
Summary
Known as metabolic arthritis, is a purine metabolic disorder caused by uric acid accumulation in and around joints. Deposited urate crystals accumulate within joints causing inflammation. Gout is more common in men with a peak incidence in the fifth decade. It is characterized by sudden, severe attacks of pain, swelling, redness and tenderness in the joints, especially the first metatarsophalangeal (MTP1) joint. Ankle and knee joints are common sites of inflammation. Few case reports of laryngeal manifestation of gout have been reported and published. Laryngoscopy revealed a hemispherical mass with a smooth surface over the right vocal process and pathology showed laryngeal gouty tophus.
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