Abstract
Postprandial plasma glucose and triglyceride concentrations are predictive of relative cardiovascular disease (CVD) risk, and the pathogenesis of both insulin resistance and atherosclerosis has been attributed to acute states of hyperglycemia and hypertriglyceridemia. Postprandial lipemia and hyperglycemia suppress vascular reactivity and induce endothelial dysfunction. Epidemiological studies suggest that chronically-high consumption of milk and milk products is associated with a reduced risk of type 2 diabetes, metabolic syndrome, and CVD. The addition of dairy products to meals high in carbohydrates and fat may lessen these risks through reductions in postprandial glucose and triglyceride responses. Purported mechanisms include dairy proteins and bioactive compounds, which may explain the inverse relationship between dairy consumption and cardiometabolic diseases. The current review evaluates the available literature describing the relationships between metabolic dysfunction, postprandial metabolism, and vascular dysfunction and discusses the potential role of milk and dairy products in attenuating these impairments.
Highlights
Fasting plasma glucose and triglyceride concentrations have been used as clinical determinants of cardiovascular disease (CVD)
An eight-week clinical trial investigating the effects of low-fat dairy intake on overweight and obese men found no effect on fasting glucose concentration [79]
The available literature describing the relationships between metabolic dysfunction, postprandial metabolism, and vascular dysfunction recognizes the role of milk, milk proteins, in reducing these clinical risk factors
Summary
Fasting plasma glucose and triglyceride concentrations have been used as clinical determinants of CVD (cardiovascular disease). Elevated postprandial plasma glucose or triglyceride concentrations following a high-carbohydrate or high-fat meal contribute to a pro-atherogenic metabolic state [9,10,11] Both postprandial lipemia and hyperglycemia are associated with reduced vascular reactivity and impaired endothelial function [12,13]. Cardiometabolic diseases through postprandial glucose triglycerides found in 1) Potential mechanisms driving this could include the proteinspossess or bioactive compounds found identification the exact component responsible for reduced postprandial in dairy. The severalofof dairy’s bioactive compounds possess functional properties glycemia/lipemia is difficult to ascertain Despite their low glycemic milk products, is the identification of the exact component responsible for reducedindex, postprandial glycemia/lipemia milk proteins, are insulinotrophic, which be a potential mechanism to explain, at least part, difficult to ascertain.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
