Abstract
Background and Aims: Perinatal transmission of hepatitis B virus (HBV) has been identified to be prevalent in most developing countries. It occurs as a result of percutaneous and per mucosal exposure to the mother's infected blood during birth. The risk of transmission however, from an infected mother to her infant is directly proportional to the viral load reflected in the serologic status of the mother. This study was therefore aimed at evaluating the use of immunoprophylaxis as well as maternal screening as a risk-reduction approach in high risk infants (Hepatitis B surface antigen (HBsAg) and Hepatitis “e” surface antigen (HBeAg) Positive mothers).
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