Abstract
Lately, concerted efforts are being investigated to invigorate intelligent polymers as they hold immense potential in various fields like polymer chemistry, materials science, pharmaceutics, bioengineering, medicine and chemical engineering. Use of stimuli-responsive in situ gelling systems such as, temperature, pH, solvent, magnetic, electric, ultra-sound and photo-polymerization has been employed for administration of drug delivery, tissue engineering, theranostic imaging and cancer therapy. With the advent of nanotechnology, the diagnosis and treatment of several complex disorders could be standardized by utilizing the enhanced permeability and retention effect and tumor-specific targeting. Nanocarriers have provided the versatile platform for the delivery of various therapeutic and diagnostic agents. Uses of nanocarrier has resolved the undesirable characteristic of anticancer drugs low solubility and poor permeability in cells. However, each system has been associated with some problems that can be minimized by using the hybrid nanocarrier systems that combine the benefits of different structural components to synergize the outcome of the therapy
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