Review of Hepatocellular Carcinoma and Liver Disease Prevalence

Abstract

Abstract: The main reason for liver-related death globally is reported as cancer which results in most patients with cirrhosis, therefore in this article, we discuss the epidemiology of liver diseases and liver cancer in the world. Ongoing review article efforts to address updated knowledge of study topics worldwide. Information on the prevalence and mortality of liver disease were extracted from Pubmed, Scopus, Web of Science and Cochrane Library. Ninety-three relevant in-depth consequent guide approaches and evidence-based choices were selected, associated with a knowledgeable collection of current, high-quality manuscripts. Research reported that around 2.3 billion people in the world are infected with one of the hepatitis viruses that could cause liver cancer. The prevalence of non-alcoholic fatty liver disease, cirrhosis and liver cancer is varied worldwide. In the United States, each year 18600 males and 9000 females die from liver cancer. The global burden of deaths due to liver cancer was reported in 830,200 in 2020 that predicted to increase to >55% by 2040. The major causes of liver cancer reported as hepatitis B (mainly in Asia) and C viruses. Regarding chronic liver disease that could cause cancer in some patients, the prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to be 6% to 35% worldwide. Steatosis and steatohepatitis affect 25% of the population worldwide. It is well known that the geographic distribution of different forms of liver disorders is divergent. Owing to population growth and ageing, liver cirrhosis and its development of cancer is an important health subject worldwide. Further studies regarding early detection of liver disease based on the easy and inexpensive test to score primary necroinflammation recommended advantageously.