Abstract
Background Cerebrospinal Fluid (CSF) pressure-volume compensatory parameters may change over time under pathological and normal circumstances. Normal ageing may affect CSF compensation: the resistance to CSF outflow increases and the formation of CSF decreases with age. In acute hydrocephalus after subarachnoid haemorrhage, baseline intracranial pressure (ICP) and resistance to CSF outflow acutely increase but they may return towards baseline over the next few weeks. Idiopathic Normal Pressure Hydrocephalus (iNPH) awaits longitudinal studies. Is NPH always the late (compensated) stage of acute hydrocephalus? Are the CSF compensatory parameters invariant in time (counting from the onset of clinical symptoms) or do they change with time?
Highlights
Cerebrospinal Fluid (CSF) pressure-volume compensatory parameters may change over time under pathological and normal circumstances
In acute hydrocephalus after subarachnoid haemorrhage, baseline intracranial pressure (ICP) and resistance to CSF outflow acutely increase but they may return towards baseline over the few weeks
Neither baseline ICP nor brain compliance nor improvement after shunting exhibited any dependence on the duration of symptoms
Summary
Address: Academic Department of Neurosurgery, Box 167 Addenbrooke's Hospital, Cambridge CB2 2QQ, UK. Published: 30 December 2005 Cerebrospinal Fluid Research 2005, 2(Suppl 1):S33 doi:10.1186/1743-8454-2-S1-S33. 1754-S419-tfhulAl.pndnfu"a>lhMereee.oocrch into Hydrocephalus and Spina Bifida Meeting abstracts – A single PDF containing all abstracts in this Supplement is available
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