Abstract
Heat shock proteins (HSP), which are widely expressed in all kinds of cells, are a set of highly conserved proteins molecules. As their expressions increase under the condition of stress, they are also called stress proteins. Studies have found that HSP play an important role in the genesis and development of various tumors. As one of the three most common malignant tumors in female reproductive system, ovarian cancer has a close relationship with HSP in the tumor genesis, development and resistance to chemotherapy. This article clarifies the biological characteristics of HSP and their relationship with the genesis, development, chemoresistance and therapy of ovarian cancer, so that it can provide reference for the treatment of ovarian cancer. Key words: Heat-shock proteins; Ovarian neoplasms; Drug resistance, neoplasm; Therapeutic uses; Treatment outcome; Women
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