Abstract

Ovarian cancer is one of the common malignant tumors, the mortality of ovarian cancer ranks first in gynecologic oncology. More and more researches suggest that ovarian cancer should be classified as stem cell diseases. The early diagnosis and early treatment of ovarian cancer depend on the detection and recognition of more ovarian neoplasm stem cell markers. In this review, we will make a review from the aspects of cancer stem cell (CSC) theory origin and its evolution, the discovery of ovarian neoplasms stem cells, ovarian neoplasms stem cells and the relationship between the ovarian neoplasms and its purification, ovarian neoplasms stem cell markers in the early diagnosis and treatment of ovarian cancer, and so on. Key words: Ovarian neoplasms; Numb protein; Cancer stem cells markers; Diagnosis; Treatment

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