Abstract
Objective To study the relevance between different results of three hemolysis detection tests and serum bilirubin levels of ABO hemolytic disease of the newborn(ABO-HDN).Methods Serological hemolysis three tests (direct anti-human globulin test,free antibody test,antibody release test),maternal anti-A (B)IgG antibodies,serum bilirubin were examined in 85 cases of ABO-HDN.Results There were significant differences in levels of total serum bilirubin (TSB) between groups of DAT-positive and groups of DAT-negative (P < 0.05,or P < 0.01).There weren' t significants difference between groups of DAT-positive or groups of DAT-negative in levels of total serum bilirubin(P > 0.05).There wasn' t significant difference between maternal antibodies titer and levels of total serum bilirubin (P > 0.05).Conclusion When DAT is positive,the serum bilirubin level was significantly increased,and maternal antibodies titer couldn' t show severity of ABO-HDN.It could be helpfull for the clinical treatment of ABO-HDN. Key words: ABO hemolytic disease of the newborn; direct anti-human globulin test; Free antibody test; Antibody release test; Serum bilirubin; Anti-A (B) IgG antibody
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