Relationship between metabolic syndrome and non-alcoholic fatty liver disease in the elderly in Dali Bai prefecture area of Yunnan

Abstract

Objective To investigate the relationship between metabolic syndrome(MS) and non-alcoholic fatty liver disease(NAFLD), to find risk factors of NAFLD and provide references for the prevention of NAFLD in patients with MS. Methods 1 024 patients were enrolled, and the patients were divided into the non-NAFLD group, NAFLD group and NAFLD+ MS group based on the physical examination outcomes.All the patients received abdominal ultrasound and blood biochemical examination, and the relationship between MS and NAFLD was analyzed. Results (1)The proportion of NAFLD was 21.39%(219/1 024), which of males was higher than that of females(30.26% vs.11.41%, χ2=26.35, P<0.01). The proportion of MS was 35.55%(364/1 024), the proportion of NAFLD in the MS group was higher than that in the non-MS group(40.66% vs.10.76%, χ2=38.16, P<0.001). With the increase of MS examination items, the proportion of NAFDL was increased (χ2=221.13, P<0.001). (2)Compared with the non-NAFLD group, the levels of BMI, WC, TG, TC, LDL-C, ALT, UA, SBP, DBP, CRP, FBG, FP, MAU, Fg in the NAFLD group and NAFLD+ MS group were higher, and the level of HDL-C in the NAFLD group and NAFLD+ MS group was lower (P<0.01-0.001). The result of logistic regression analysis showed that WC, BMI, high TG, high UA were independent risk facts for the prevalence of NAFLD. Conclusion There is close association between NAFLD and MS, and WC, BMI, TG, SUA are risk factors of NAFLD. Key words: Fatty liver; Metabolic syndrome X; Aged