Abstract
The aim was to define reference ranges for cerebral oxygen saturation (crSO2-ROOT) during immediate transition after birth in stable neonates. In a prospective observational study, the crSO2-ROOT was continuously measured in neonates during the first 15 min after birth. The neonatal sensor was placed on the head and fixed with a bandage. Median values and 10th and 90th centiles were calculated for each minute. Additionally, cerebral fractional tissue oxygen extraction (cFTOE-ROOT) was calculated using crSO2-ROOT and arterial oxygen saturation (SpO2) measured with pulse oximetry. These crSO-ROOT values were compared with already published reference ranges of cerebral oxygen saturation measured using different devices: crSO2-INVOS and cTOI-NIRO. The data of 122 neonates (14 preterm/108 term neonates) were analysed. The crSO2-ROOT values had a similar course when compared to cTOI-NIRO values, whereas crSO2-INVOS values were initially lower and exceeded during the first minutes after birth. The present observational study added reference ranges of crSO2-ROOT in stable neonates immediately after birth. As there are differences regarding reference ranges of various near-infrared spectroscopy (NIRS) devices, it is important to be aware of this information for future clinical use.
Published Version
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