Abstract
Although new concepts in the preparation of samples for liquid scintillation counting have not emerged, some improvements have been made. We now have, for example, a range of solubilizing agents which are more effective and less quenching than Hyamine -hydroxide and we can count several milliliters of aqueous material where, previously, we were restricted to a few microliters. In the area of combustion techniques we have traveled a route which started from tedium with a touch of hazard and is now firmly headed for automated convenience. What has also changed is the application of liquid scintillation counting to samples generated by current analytical techniques such as gel electrophoresis and radioimmunoassay. Certainly a new dimension to radioisotopic techniques has been added by the recognition that energetic beta-emitters such as can be counted directly in a liquid scintillation counter by Cerenkov radiation. A sample for liquid scintillation counting consists of 4 components: 1) the solvent 2) scintillator 3) sample 4) the sample container or counting vial.
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