Abstract
Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.
Highlights
Mycotoxins are secondary metabolites produced by microscopic and macroscopic fungi which can contaminate food crop, or entire food crops, throughout the food chain
Ochratoxin-A [7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products
This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and the current approaches for detecting OTA in food products
Summary
Mycotoxins are secondary metabolites produced by microscopic (micromycetes) and macroscopic (macromycetes) fungi which can contaminate food crop, or entire food crops, throughout the food chain. Fungal toxins are produced by species within the genera Fusarium, Aspergillus, and Penicillium, which frequently occur in crops or during storage of food [1] These mycotoxins have deleterious effect on agricultural productivity, human health (including carcinogenesis, immune suppression, teratogenicity), growth retardation, and animal toxicities including the possible carry-over of mycotoxins or their metabolites into the human food chain [1]. OTA, OT-B & C, aflatoxin B1, B2, B3 & M1, citeroviridin, patrulin, citrinin and zearalenon are widely studied due to their known adverse effect on human/animal health though food and beverage consumption. Among these OTA has gained much attention recently.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
