Abstract
ABSTRACT Two two-component mixtures have been assayed using both Vierordt's method and ratio-spectra zero-crossing derivative spectrophotometric methods. Such mixtures are hydrochlorothiazide-spironolactone and hydrochlorothiazide-ramipril. These selected applications illustrate the relative ease and simplicity offered by ratio - spectra zero - crossing derivative spectrophotometry for the assay of two component mixtures with spectral interferences from matrix formulations.
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