Abstract
Abstract In this paper, two-component mixtures (spironolactone with hydrochlorothiazide, captopril with hydrochlorothiazide, and spironolactone with furosemide) were assayed by U.V. (A), first derivative (dA/dlD) and second derivative (d2A/dlD2) spectrophotometric methods, applying “Zero-Crossing” technique of measurement. The methods were proved using laboratory prepared mixtures. The utility of the methods in assay of dosage forms is also presented.
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