Abstract
A simple, fast, and reliable method was established for simultaneous determination of 43 pesticides in Schizonepeta tenuifolia. The samples were prepared using solid-phase extraction (SPE) method. Pesticides were extracted from Schizonepeta tenuifolia using acetonitrile, cleaned with Pesticarb/NH2, and eluted by mixed solvents of acetonitrile and toluene (3 : 1, v/v). Selected pesticides were identified using DB-35MS capillary column and detected by gas chromatography mass spectrometry. Samples were quantified by external standard method. Recoveries for the majority of pesticides at spike levels of 0.2, 0.5, and 1 mg kg−1 ranged between 70 and 120% (except for Chlorothalonil, Thiamethoxam, and Dicofol), and the relative standard deviations (RSDs n = 6) were 1.32%–13.91%. Limits of detection (LODs) were 0.0011–0.0135 mg kg−1, whereas limits of quantification (LOQs) were 0.0038–0.0451 mg kg−1. The satisfactory accuracy and precision, in combination with a good separation and few interferences, have demonstrated the strong potential of this technique for its application in Schizonepeta tenuifolia analysis.
Highlights
Chinese herbal medicines (CHMs) have been widely used as a means of medication for their mild pharmaceutical effects and minimum side effects [1]
Due to the complex nature of the matrices in which the target compounds are present and the low detection levels required by regulatory bodies, efficient sample preparation is an important aspect of analytical methods [2]
A rapid sample preparation for multiresidues detection in Schizonepeta tenuifolia was developed by dispersive solid-phase extraction technology
Summary
Chinese herbal medicines (CHMs) have been widely used as a means of medication for their mild pharmaceutical effects and minimum side effects [1]. What is more, they have been considered to be gentle, nontoxic, and even harmless mainly because of their natural origin [2]. Schizonepeta tenuifolia is one of the most frequently used crude drugs for oriental medicine in China, Korea, Japan, and other Asian areas. It plays an important role in agricultural production and people’s living. Pharmacological studies and clinical practice have proven that it is used as an antipyretic, analgesic, antipathogenic microorganisms, antiinflammatory, antioxidation, and hemostasis drug for the treatment of colds, headaches, measles, rubella, sores, etc
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