Abstract
Radiation therapy (RT) is a newly evolving option in the treatment of both primary and metastatic liver cancer. To understand how RT can be applied to liver cancer and potential future directions of treatments, a review of the literature was performed.
Highlights
Primary liver cancer is the fastest growing cancer in Canada, with the incidence rate increasing by almost 4% per year in males and 3% per year in females since 1970, and is the third most common cause of cancer death worldwide.[1]
Hepatitis B and C viruses (HBV and HCV) are known to be oncogenic[1] and it is possible that some of the increase in the rates of liver cancer in North America is a result of increased immigration from countries where HBV is endemic;[2] half of all cases of hepatocellular carcinoma (HCC) in North America are not related to HBV or HCV.[3]
Patients with very early-stage primary liver cancer are typically treated with surgical resection, resulting in a 90% five-year survival rate.[14]
Summary
Primary liver cancer is the fastest growing cancer in Canada, with the incidence rate increasing by almost 4% per year in males and 3% per year in females since 1970, and is the third most common cause of cancer death worldwide.[1].
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