Abstract

A specific high-performance liquid chromatographic method has been developed for quantitative analysis of indapamide in solid pharmaceutical dosage forms on the Turkish market. A LiChrospher RP-18 column, HP-1050 UV-detector and acetonitrile-distilled water (35:65) as the solvent system were used. The flow-rate was 1.5 mL min−1. Quantitative determination of indapamide was carried out at 254 nm. The method was found to be rapid (under 10min per assay) and was selective enough to allow the determination of indapamide in the presence of certain excipients.

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