Abstract

Medicinal plants have long been recognised as valuable resources for traditional medicine and modern pharmaceutical research due to their rich reservoirs of bioactive compounds. This study aims to provide baseline data on the phytochemical content and antioxidant activity of a tropical medicinal shrub, Miconia crenata, from Ayer Hitam Utara Forest Reserve (AHUFR), Muar, Johor. Total flavonoid content was determined by using the chloride colorimetric method, while antioxidant activity was validated by the DPPH radical scavenging assay. Phytochemical screening of the methanol extract from the leaves of M. crenata revealed the presence of secondary metabolites, including phenols and flavonoids. The total flavonoid content was measured at 508.84 ± 154.42 mg/mg at a concentration of 0.02 mg/mL, while the extract demonstrated high antioxidant potential, with an IC50 value of 40.54 μg/mL. Further investigation into the phytochemical content of M. crenata may unlock valuable insights into its potential therapeutic uses and contribute to the development of novel pharmaceuticals and natural health products.

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