Abstract
Three cases of pyoderma gangrenosum complicating chronic non-specific ulcerative colitis are described in detail. No pathognomonic flora was found and some of the purulent lesions were sterile. Large quantities of sulfonamides and penicillin were of no value either prophylactically or therapeutically. Improvement in Case I followed improvement of the general condition of the patient and persistent local therapy with ultraviolet light and silver nitrate solutions. Complete recovery in Case II was achieved after resection of the infected colon and restoration of a normal state of nutrition. The third patient recovered after use of ultraviolet light therapy, local application of tincture of gentian violet and control of the chronic non-specific ulcerative colitis.
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