Abstract
The research conducted by the methods of contact computer biomicroscopy and cross-polarization optical coherent tomography allowed to assess the microcirculation, and inflammatory and fibrosing process in the oral mucosa in patients with chronic inflammatory bowel diseases (Crohn's disease and chronic nonspecific ulcerative colitis), to determine the frequency of certain morphological features and to reveal the differences between the individuals examined. The increase in the arteriolar and venular diameters of capillaries, deformation, haziness, and blurriness of microvascular picture of the oral mucosa in patients with chronic inflammatory bowel diseases showed the angiopathy development, being higher in patients with Crohn's disease as compared to individuals suffering from chronic nonspecific ulcerative colitis. Microstructural changes of the oral cavity mucosa in patients with Crohn's disease in comparison with the control groups and individuals with chronic ulcerative colitis are characterized by an excessive accumulation of collagen in the connective tissue stroma.
Highlights
Petersburg; 3 Kursk State Medical University, Kursk The research conducted by the methods of contact computer biomicroscopy and cross-polarization optical coherent tomography allowed to assess the microcirculation, and inflammatory and fibrosing process in the oral mucosa in patients with chronic inflammatory bowel diseases (Crohn's disease and chronic nonspecific ulcerative colitis), to determine the frequency of certain morphological features and to reveal the differences between the individuals examined
The increase in the arteriolar and venular diameters of capillaries, deformation, haziness, and blurriness of microvascular picture of the oral mucosa in patients with chronic inflammatory bowel diseases showed the angiopathy development, being higher in patients with Crohn's disease as compared to individuals suffering from chronic nonspecific ulcerative colitis
Microstructural changes of the oral cavity mucosa in patients with Crohn's disease in comparison with the control groups and individuals with chronic ulcerative colitis are characterized by an excessive accumulation of collagen in the connective tissue stroma
Summary
Проведено обследование 64 стоматологических больных с хроническими воспалительными заболеваниями кишечника в возрасте от 20 до 69 лет. В соответствии с основным соматическим заболеванием сформированы две группы обследуемых лиц:. I группа – с болезнью Крона (34 человека в возрасте от 20 до 63 лет) и II группа – с хроническим неспецифическим язвенным колитом (30 человек в возрасте от 22 до 69 лет). Контрольная группа практически здоровых лиц составляла 20 человек в возрасте от 19 до 72 лет. При исследовании слизистой оболочки полости рта обследованных лиц применены методы контактной компьютерной биомикроскопии (ККБ) и кросс-поляризационной оптической когерентной томографии (КП ОКТ) [17]
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