Prospects of zinc nano oxide application in the treatment of purulent wounds.

Abstract

Surgical infection is a difficult problem in modern medical practice. Prevalence of surgical infection, new strains of microorganisms and their resistance to antibiotics, poor outcomes of wound treatment, lack of sensitivity of microorganisms to commonly used antiseptics necessitate the search for the new methods and means of treatment in wound surgery. This article provides an overview of domestic and foreign literature on the possibility of solving the problem of effective local treatment of purulent wounds through the study and implementation of nanotechnology in modern medicine. Researchers around the world are beginning to use nanoparticles and developments of nanotechnology in various fields of science and medicine to synthesize new drugs and vaccines, including zinc nano oxide usage as a highly effective local antiseptic that is non-toxic to the cells of the human body at very low, concentrations but with sufficient antibacterial action. Small sizes and large surface area relatively to volume increases efficiency of interaction of nanoparticles with germs and makes it probable a wide range of antimicrobial activity. Nanoparticles on metals base due to their biological and physical-chemical properties are perspective antibacterial agents and may be used to solve many problems in nanomedicine and surgery in particular. Study and application of zinc nano oxide in preparations of multidirectional local action will ensure high effective defense against pathogenic microorganisms in the wound.