Abstract

Active Rac1 are so imp for improving cytoskeletal systems and necessary for activating IFN-beta & Plcγ2 (which are necessary for regulating TXA2 Synthesis), and are playing imp role for activating CMs and endothelial cells through Ang1 synthesis (mediated by Gp GTP subunits synthesis) then followed by tyrosine kinases function (contain TAT and TAC codons) for Ang2-AT2 productions for adjusting heart contractions and preventing collagen, glycoproteins, and cholesterol accumulations. Angiotensin II type 2 receptors (AT2 receptors) play a modulatory role in blood pressure regulation but produced from Ang1-AT1 by ACE regulated functions , where Tyr codons are playing imp roles in AT1 and AT2 activities and can play so important roles in protecting heart and blood vessels from accumulated cholesterol and glycopeptides and from accumulated glycogen. AT1 receptors promotes the adjustment of various intracellular signaling pathways through Ang2-AT2 production resulting in hypertension, endothelial dysfunction, and recovering the cellular damage.

Full Text
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