Abstract
Proliferative verrucous leukoplakia (LVP) is a rare type of oral leukoplakia with slow growth and high potential for malignancy, with female predilection in the sixth decade of life. The aim of this report is to describe the clinical and histopathologic findings of a case of LVP. A 52-year-old male patient, an alcoholic since 12 years old, sought the health service because of an asymptomatic lesion with a 1-year evolution. The intraoral examination revealed multiple bilateral whitish plates with clear borders and verrucous surface located in jugal mucosa and labial commissure. The initial diagnostic hypothesis was verrucous carcinoma. An incisional biopsy was performed, and the histologic slices revealed fragments of mucosa coated by hyperkeratinized squamous epithelium with a verrucous surface corresponding to LVP. The patient is stable and under follow-up. The importance of early diagnosis and routine follow-up of patients because of the high rates of malignant transformation is emphasized.
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