VERRUCOUS CARCINOMA, A VARIATION OF SQUAMOUS CELL CARCINOMA: A CASE REPORT WITHOUT RELATION TO CARCINOGENIC FACTORS

Abstract

Oral squamous cell carcinoma is a malignant neoplasia, which emerges from keratinocytes more often related to advanced age, smoke and drink habits. It presents several clinical-histopathological variants that include verrucous carcinoma (VC). The objective of this work is to report a case of a female, 31-year-old, leukoderma, non-smoker and non-drinker, with the chief complaint of a wound in her mouth. Extraoral examination no alterations were observed. Intraoral inspection revealed a single reddish ulcerated lesion with white borders with sharp edges, located in the right side of buccal mucosa, with oval shape and verrucous surface, painless and without apparent infiltration. Clinical hypothesis diagnoses were VC and paracoccidioidomycosis. An incisional biopsy was performed, and the histopathological sections stained with hematoxylin and eosin showed a malignant neoplasm of epithelial origin with verrucous surface. This case highlights the importance of diagnosis of VC in a young non-smoker and non-drinker patient. Oral squamous cell carcinoma is a malignant neoplasia, which emerges from keratinocytes more often related to advanced age, smoke and drink habits. It presents several clinical-histopathological variants that include verrucous carcinoma (VC). The objective of this work is to report a case of a female, 31-year-old, leukoderma, non-smoker and non-drinker, with the chief complaint of a wound in her mouth. Extraoral examination no alterations were observed. Intraoral inspection revealed a single reddish ulcerated lesion with white borders with sharp edges, located in the right side of buccal mucosa, with oval shape and verrucous surface, painless and without apparent infiltration. Clinical hypothesis diagnoses were VC and paracoccidioidomycosis. An incisional biopsy was performed, and the histopathological sections stained with hematoxylin and eosin showed a malignant neoplasm of epithelial origin with verrucous surface. This case highlights the importance of diagnosis of VC in a young non-smoker and non-drinker patient.