Abstract
The occurrence of cervical cancer is the result of long-term synergy from a variety of carcinogenic factors. Human papilloma virus (HPV), the main biological cause of cervical cancer, is closely related to the occurrence of cervical cancer, while HPV E6/E7 protein plays an important role in the malignant transformation of cervical cancer. This article summarizes the carcinogenic mechanism of HPV E6/E7 and application in cervical cancer screening, and reviews the targeting therapy aiming at HPV E6/E7. Key words: Human papilloma virus; E6/E7 protein; Cervical neoplasms; Targeting therapy
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