Principles of Biomimetic solid-state nanopores and the application to biosensors

Abstract

The wide application of biomimetic solid-state nanopores in biosensors has made them a high-profile research area. It can be applied in several fields such as genomics, proteomics, biomedicine, and environmental monitoring. Bionic solid-state nanopores have demonstrated the capability to detect biomolecules and creatures, including proteins, nucleic acids, cells, and microbes, with a notable degree of sensitivity and selectivity. Biomimetic solid-state nanopores offer several advantages over conventional biosensors. An innovative kind of biosensor is called biomimetic solid state nanopores. This study provides a comprehensive overview of the principle, construction, and use of the bionic solid state nanopore sensor. Bionic solid-state nanopores are of significant importance within the realm of biosensors. Firstly, it has micrometer or nanometer scale, which can effectively capture and control target molecules; Additionally, the dimensions of the biomimetic solid-state nanopores can be modified, along with the surface functionalization, in order to enhance the performance of the sensor and expand its potential applications. In addition, the structural stability and reusability of biomimetic solid-state nanopores also guarantee the long-term application of biosensors. Through in-depth research and development, it is expected to promote the technological progress in the field of biosensors, and provide more accurate and reliable detection methods for life science, medical diagnosis, environmental protection and other fields.