Abstract
Abstract Extraskeletal osteosarcoma is a rare malignant soft tissue tumour, which represents about 4% of all osteosarcomas and 1% of all soft tissue sarcomas. We present a case of extraskeletal osteosarcoma, albeit at a hitherto
Highlights
Extraskeletal osteosarcoma is a malignant mesenchymal neoplasm that depicts malignant osteoid, bone and/or chondroid material
We present a remarkable case of primary duodenal extra osseous osteosarcoma
The biological behaviour of well differentiated extraskeletal osteosarcoma has been suggested to be better than that of classical extraskeletal osteosarcoma, but some cases can progress to a higher grade [7]
Summary
Extraskeletal osteosarcoma is a malignant mesenchymal neoplasm that depicts malignant osteoid, bone and/or chondroid material. These tumours have no attachment to bone or periosteum, which has to be determined by the examination of radiological findings or observation during surgery [1,3]. Computed tomography of the abdomen revealed a large bulky mass involving duodenal and paraduodenal region with cholelithiasis (Figure 1). Endoscopic findings revealed a submucosal mass with superficial ulceration of duodenal mucosa. Microscopic examination revealed a cellular tumor involving the sub mucosa, muscularis propria and subserosa of the small intestinal wall with superficial mucosal ulceration. Areas of osteoid were seen between the tumor cells with scattered osteoclastic giant cells (Figures 3A and 3B). The patient had an uneventful post operative period and remains free of tumor a year after surgery
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